Methylene blue is a chemical compound frequently used as a dye in medical procedures and functions as a vasopressor. It acts as an inhibitor for guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). Methylene blue influences the nitric oxide synthase/guanylate cyclase signaling pathway and is capable of crossing the blood-brain barrier. It also functions as a Tau aggregation inhibitor, demonstrating potential in reducing cerebral edema, attenuating microglial activation, and diminishing neuroinflammation.
- Inhibits sGC, MAO-A, and NOS pathways
- Used as a vasopressor and medical dye
- Influences nitric oxide synthase/guanylate cyclase signaling
- Crosses the blood-brain barrier
- Functions as a Tau aggregation inhibitor
- Reduces cerebral edema and neuroinflammation